Program Summary: Amitabha ‘Guppy’ Gupta, PhD, “Updates on COVID-19 and New Research at Fred Hutch,” July 8, 2021

Submitted by Lee Raaen

The club was privileged to have Dr. Gupta of the Fred Hutchinson Cancer Research Center present an encore performance regarding research and advancements in the treatment and prevention of COVID-19 and cancer.

He pointed out that when he last spoke to the club about 11 months ago, a vaccine for COVID-19, particularly mRNA vaccines were mostly a theory. In a short time not only have vaccines been developed, but a large percentage of the population of the country has been vaccinated. King County is fortunate to have approximately 74% of people over the age of 16 vaccinated. Of course far more needs to be done to vaccinate unprotected populations not only in this country but around the world.

South King County has a lower vaccination rate than other areas of the county. This segment of the population has not yet reached the 70% level. Systemic racism and related its economic and other consequences are factors.

While Fred Hutchinson is known for its research into cancer, it is also very involved in the research and development of COVID-19 vaccines. Approximately 20% of their research resources are devoted to COVID.

Dr. Gupta explained the process of the development of COVID variances, and the relative concerns of the A, D, B and G variances first noticed in different countries around the world. The D variance is now the one most of concern here. Approximately 50% of new infections in the US are of the D variance. This is particularly true in low vaccinated areas. The good news is that the Moderna and Pfizer vaccines appear to be effective against this variant.

He explained that it is unknown if or to what extent someone who is fully vaccinated can still transmit the virus. As a result, safety precautions are still advisable by people who are vaccinated but interact with those who are too young or medically unable to receive the vaccines. He personally wears a mask around people indoors who may not be completely vaccinated.

Dr. Gupta for the second portion of his talk offered four alternative topics. The “winning topic” by a poll of the membership was “Harnessing the Immune System to Cure Cancer.” He presented a fascinating look into the use of the modification of T cells and T cell receptors in the fight against cancer. He pointed out that a normal function of T cells is to identify and destroy individual cells in the body which are in some way defective. They are researching  the use of that function to target cancer cells. The Hutch has had success in using this approach in blood cancers, but because of the structure and environment of solid tumors, it does not work well with those cancers. Research into modifying cells, including the use of Crispr technology, is attempting to reengineer cells to use the T cell function in solid tumor cancers.

Once again, “Guppy” provided an interesting and informative presentation to our club membership and visitors.

Dr. Amitabha (Uh-Myth-aabh) “Guppy” Gupta got his Ph.D. in Cellular, Molecular, and Biophysical Sciences from Columbia University before moving to the Fred Hutchinson Cancer Research Center to do his post-doctoral research. While he was doing his American Cancer Society-funded research and applying to be a teacher at a small liberal arts school, the Hutch convinced him to stay and talk about their research. He currently serves as the Scientific Content Strategist for the Philanthropy Department, where he keeps his finger on the pulse of the research going on at the Hutch, and helps translate it to the general public.

Father Full Families Virtual Banquet, June 12, 2021

Marvin Charles of DADS was a speaker at our club last summer.

 
ONE WEEK AWAY!
Father-Full Families
2021 DADS Fatherhood Virtual Event  
Launch June 12, 2021, 5:00pm, look out for the link in your inbox on June 12th.
JOIN THE FUN OF OUR CREATIVE RAFFLE
     
You can win a $100 gift card to Top of The Hill Produce and a swag bag!  There will be two opportunities to win.  Look for more details in your confirmation page or contact Rosa TODAY.     We look forward to seeing you on Saturday, June 12th, where you will hear stories about Father-Full Families during the week leading up to your own Father’s Day celebration!  

VERY IMPORTANT! – If you are a Watch Party Host, make sure your friends and family watching with you REGISTER for this event as a watch party guest – remember it’s FREE– click the link NOW www.aboutdads.org. By registering, you’ll be signed up to receive details to the RAFFLE and the private video link when we launch.   

HOW TO HOST A WATCH PARTY:  CALL ROSA NOW! IT’S NOT TO LATE (206) 949-1219

Sincerely,    Rosa Nicole Booker 206-949-1219 info@aboutdads.org  
P.S.   Cost: FREE!    
Several sponsorship levels are still available.   Call or email for Registration and Sponsorship questions.          
Helpful Links   Register as: An Individual, Watch Party Guest, or Watch Party Host   Register as a Virtual Event Sponsor   Donate   Questions

Address postal inquiries to:

Divine Alternatives for Dads Services

5709 Rainier Ave S
Seattle, WA 98118-2703

Program Summary: Bud Ransom, Ravenna Brewing, May 20,2021

May be an image of drink

Bud Ransom grew up in Bellingham, WA before moving to Seattle to attend Cornish College as a music composition major. Through college and after graduating he worked as a craft cocktail bartender, until 2016 when he founded Ravenna Brewing Company with his sister and brother-in-law. As owner and operations manager he’s guided their growth from a tiny nanobrewery into the award-winning distribution microbrewery and taproom they are today.

Key Points Summary by Michelle Lee

Bud did bartending while going to Cornish College.  He and his sister, Elise, had been thinking about starting some sort of eatery like a café, while his brother-in-law, Tommy, was a home brewer accumulating recipes and winning awards…… thus the three of them founded a brewery.

They found a location in the Ravenna neighborhood.  The space was in rough condition and no plumbing, but it was cheap.  They did not have any cash flow and basically did the tenant improvement themselves through watching YouTube videos.  Bud and his dad did the drawing themselves with an architectural scale ruler to apply for permit.  During construction, Bud made sure he would stop and talk to anybody who came by, showed them the progress and talked about what beer were being brewed.  This interrupted the progress but helped build neighborhood support that growlers were filled even before the official opening.   

Thanks to a post on Seattle Reddit, the line went out the door and around the block on the grand opening date April 15, 2016.  The brewery only opened from Thursday to Sunday in the beginning, then added Wednesday in August and then had its first trivia Tuesday in January 2017.  After the first year build out and six months in operation, Bud, Elise and Tommy finally got their first paychecks.

In mid-2018, their landlord told them the next door space was available.  They might not be ready to expand and they also knew that they had to take over the space which might not be available again.  The extra space could also help solve the capacity problem, they could not brew fast enough especially for the very busy summer.  In August 2019, their expansion was completed.  Their fermentation capacity increased almost 3 times from 868 gallons to 2,263 gallons.  They thought that they would have a smooth and easy summer in 2020.

Then it same the pandemic shutdown on March 15, 2020.  They knew that they needed to continue the momentum and served their customers.  They did not shut down for one day and kept working on the growler machine. With the loyal neighborhood support, they had beer-to-go.  To survive the pandemic, they did not rest and stayed aggressive.  In August and October 2020, they further increased their fermentation capacity to 3,441 gallons and added automatic canning line to meet the pandemic induced demand for to-go beer and diversify to wholesale.

Again in November 2020, during the second big wave of pandemic, another next door space became available for sale, they knew that they needed to make it happen.  The additional space will serve as a brewing space, a private party space and office space, so that Bud and Elise do not need to work from their backpack anymore. The fermentation capacity will be 5,983 gallon, almost 7 times the original capacity, when this expansion is completed in August 2021.

Why it worked:

  • Service at the forefront of everything – Bud is sensitive in cultivating a warm and welcoming atmosphere and in building the community.
  • Partnership with opposing strengths, but equal drive – Tommy and Bud are different people, “without Tommy, they could not open the brewery; without Bud and Elise, the brewery would have been burnt down by now”. 
  • Hire the person, not the resume – only 3 people quit in their 5-year history due to moving to Colorado or finding a full time job for what they went to college for.
  • Don’t be afraid to be trendy – they brew what people want and have not repeated a recipe.
  • Empower, reward, and retain talent – employee are allowed to have flexible working hours to go back to school or part time, can move to operation management or distribution if interested.

According to one review on Yelp:

Excellent beer, excellent people. This neighborhood brewery worked hard to spruce up a small shop into a great place to enjoy some beer. As of opening weekend they have come out with some inventive brews such as a Jalapeño Kölsch, a Peach Hefeweizen, and a Bourbon Vanilla Porter. Don’t let the fancy names scare you off though. Clean, balanced flavors and reasonable prices rule here; they pour both 16oz pints (around $5-6) and 5oz tasters (around $2-2.5). Growler fills coming soon; their supply needs to catch up with their overwhelming opening weekend demand.

While they don’t have a kitchen, they have partnered with food trucks who park right outside and serve their wares.

Come by, say hello, have a beer, and enjoy!

Big Taste Update

We are now planning to resume The Big Taste event in April 2022–after a two-year layoff.

To host a fun and fundraising community tasting event, best-matched for what we’ve successfully produced in the past at Hanger 30 at Magnuson Park, we’re agreeing to look for The Big Taste to occur next in 2022 – probably on a Saturday in April, but possibly early May or late March.

Our beneficiary is Outdoors for All. In support of that, here’s a photo of Milo and his parents. Club member and Outdoors for All Executive Director Ed Bronsdon met them recently at Magnuson Park as they were using one of the many adaptive cycles, a Duet Tandem, that Outdoors for All has in their fleet. Ed reported that, “Due to public health restrictions, it had been eighteen months since Milo and his family had last been able to be active with our Adaptive Cycling Center. Milo had fun – but his parents, Erik and Kim, I think were even more joyous in getting outdoors together as a family. They noted that they plan to be back regularly now that we are able to be back up and operational and really appreciated the ride with us. The Outdoors for All Staff were sure smiling, too!”

Join Us IN PERSON for our Annual President’s Dinner!

Date – Time – Place

See the source image

Sunday, June 6, 2021, 5:00 PM, at the Seattle Yacht Club (1807 E. Hamlin Street, Seattle, WA 98112 — 206-325-1000)

Business casual attire appropriate.  No blue jeans per SYC dress code.

RSVP required (to Nancy Bittner 206-595-9620) by Monday, May 24th!

If you have not already been called, please call or text Nancy if you plan to attend.  She will need to know what choice you would like for your dinner entree, either beef, fish, or vegetarian.

Cost – Payment – Money Q&A’s

Dinner is $65/person.  Payment by credit card or check the night of the event.

CASH is needed to purchase “script” if you wish to purchase wine, beer, hard alcohol, or soft drink prior to dinner.  Wine will be provided with dinner.  CASH will also be needed to purchase raffle tickets which are $5 each or 5 for $20.

HOW CAN YOU CONTRIBUTE?

We would appreciate every member to procure or buy a gift card or donate a nice bottle of wine (or scotch) for the raffle.  You decide the amount that works for you.  As in every fundraising event, including this one, there will be a RAISE THE PADDLE component.  Please put some thought into this and give what fits into your budget.  (Last year we raised a record $11,000 in this category & that was virtually!  Let’s see if we can beat that this year!)

The most important thing of all is to HAVE FUN in the fellowship of Rotary!

Program Summary: Cyrus Krohn, “Bombarded: How to Fight Back Against the Online Assault on Democracy,” May 6, 2021

Imagine an imminent America where citizens are bombarded with personalized political messages from every smart device – yet information is so suspect, nobody can tell what the truth is.

The coronavirus pandemic provided a foretaste of an infuriating, dystopian future. From the start Americans fought over the most basic facts of the crisis, from death tolls to quack cures to the wisdom of stay-at-home orders. The splintered digital infosphere bred confusion and delusion, some of it fatal. Now think of our campaigns and elections. The digital information age means more than hyper-targeted, just-for-you messages from insurance companies and presidential candidates alike. It means oceans of disinformation engineered to sow false beliefs or simply disorient.

Big Data is on the way to fueling information environments so fine-tuned, no two of us hold the same view of reality, and no two voters hear the same pitch. Already, citizens don’t know who to trust or what to believe – about COVID-19 or anything else. If we ask nothing more of tech providers or digital citizens, the fog will continue to thicken. Irritation will merge into despair and then numbness… and democracy teeters.

Digital pioneer Cyrus Krohn knows the territory, and in Bombarded: How to Fight Back Against the Online Assault on Democracy, Krohn locates the roots of our blooming political chaos. But he goes beyond recounting 25 years of destabilizing Internet shock waves and rolls out a provocative action plan for rescuing the American system of campaigns and elections while there is still time.

Bombarded was recently selected as a finalist for INDIE “Book of the Year” by Foreword Reviews.

You can get the book on Amazon here. Learn more about the book here.

Key Points Summary by Michelle Lee

After interning at the White House, working on CNN’s Larry King Live and Crossfire, Cyrus has insights about social media and privacy.

In 1996, Bill Gates predicated the media on paper would be out.  Nowadays, we have social media instead.  Contrary to the clean broadcast debate such as Crossfire, there is no single source of truth or no reliable narrator on social media.

Regarding privacy, our consumer purchase habit and financial well-being collected as 3000 attributes, can be easily bought.  This was what Cambridge Analytica bought for about 300 million Americans from Facebook.  Technology is being built, data are being harvested and used for political campaigns.

There are two major laws tech companies follow – CCPA from California and GDPR from EU.  Washington State tried to pass a state privacy law in 3 attempts but failed.  Cyrus would like to see a Federal Data Privacy Act.  It would be difficult for businesses if there are 50 from the states.

Cyrus also thinks that government and civic education should be added back to the curriculum.  So that people will know how our government functions and be active and viable participants.  Lastly, he encourages us to participate in local journalism, attending school boards and city councils meetings, write and publish the facts, as most of the local newspapers are lost and people use social media for local news.    

Words to Live By: George Carlin

“The paradox of our time in history is that we’ve learned how to make a better living, but not a better life. We have more conveniences but less time, wider freeways but narrower viewpoints, more medicine but less wellness. We’ve been to the moon and back, but have trouble crossing the street to meet a new neighbor or to help a stranger in need. We’ve conquered the atom, but not our prejudice.

So put down the phone and the remote, and look at the world around you. Spend time with your loved ones, because they won’t be around forever. Take the time to make a new friend, to say a kind word, to do something selfless. And always remember, life is not measured by the number of breaths we take, but by those moments that take our breath away.”

           – George Carlin